Other Information: Store at room temperature 68 degrees - 77 degrees F. Protect from freezing. Misc: Previously available only by prescription. FDA approved. Dermatologist developed. Once daily topical retinoid (read consumer information leaflet before use). First FDA-approved over-the-counter topical retinoid (read carton and enclosed consumer information leaflet before using this product. Keep this carton and consumer information leaflet. They contain important information). Oil free. Fragrance free. Dermatologist developed and tested. Made in Canada.